File Name: introduction and history of immunology .zip
- Immunity (medical)
- An introduction to immunology and immunopathology
- Atlas of Immunology
- Immune system
Data sharing not applicable to this article as no datasets were generated or analyzed during the development of this review. Beyond structural and chemical barriers to pathogens, the immune system has two fundamental lines of defense: innate immunity and adaptive immunity. Innate immunity is the first immunological mechanism for fighting against an intruding pathogen. It is a rapid immune response, initiated within minutes or hours after aggression, that has no immunologic memory.
Immunology has its origins in the study of how the body protects itself against infectious diseases caused by microorganisms, such as bacteria, viruses, protozoa, and fungi, and also parasitic organisms, such as helminth worms. Important initial barriers to infection are physical e. The internal mucosal tissues e. In the airways, mobile ciliate hairs work together to transport contaminants away from vulnerable areas. Tissues such as the skin, mucosal surfaces and airways also contain populations of immune cells that can respond to infectants that breach these physical defences.
Vaccine , suspension of weakened, killed, or fragmented microorganisms or toxins or of antibodies or lymphocytes that is administered primarily to prevent disease. A vaccine is made by first generating the antigen that will induce a desired immune response. The antigen can take various forms, such as an inactivated virus or bacterium, an isolated subunit of the infectious agent, or a recombinant protein made from the agent. The antigen is then isolated and purified, and substances are added to it to enhance activity and ensure stable shelf life. The final vaccine is manufactured in large quantities and packaged for widespread distribution. A vaccine delivery system is the means by which the immune-stimulating agent constituting the vaccine is packaged and administered into the human body to ensure that the vaccine reaches the desired tissue. Examples of vaccine delivery systems include liposomes, emulsions, and microparticles.
Metrics details. In basic terms, the immune system has two lines of defense: innate immunity and adaptive immunity. Innate immunity is the first immunological, non-specific antigen-independent mechanism for fighting against an intruding pathogen. It is a rapid immune response, occurring within minutes or hours after aggression, that has no immunologic memory. Adaptive immunity, on the other hand, is antigen-dependent and antigen-specific; it has the capacity for memory, which enables the host to mount a more rapid and efficient immune response upon subsequent exposure to the antigen. There is a great deal of synergy between the adaptive immune system and its innate counterpart, and defects in either system can provoke illness or disease, such as autoimmune diseases, immunodeficiency disorders and hypersensitivity reactions. This article provides a practical overview of innate and adaptive immunity, and describes how these host defense mechanisms are involved in both health and illness.
An introduction to immunology and immunopathology
The immune system is a network of biological processes that protects an organism from diseases. It detects and responds to a wide variety of pathogens , from viruses to parasitic worms , as well as cancer cells and objects such as wood splinters , distinguishing them from the organism's own healthy tissue. Many species have two major subsystems of the immune system. The innate immune system provides a preconfigured response to broad groups of situations and stimuli. The adaptive immune system provides a tailored response to each stimulus by learning to recognize molecules it has previously encountered. Both use molecules and cells to perform their functions.
In biology, immunity is the capability of multicellular organisms to resist harmful microorganisms. Immunity involves both specific and nonspecific components. The nonspecific components act as barriers or eliminators of a wide range of pathogens irrespective of their antigenic make-up. Other components of the immune system adapt themselves to each new disease encountered and can generate pathogen-specific immunity. Immunity can be defined as a complex biological system endowed with the capacity to recognize and tolerate whatever belongs to the self, and to recognize and reject what is foreign non-self. The immune system has two components: innate and adaptive immunity.
PDF | In basic terms, the immune system has two lines of defense: innate immunity and adaptive immunity. Innate immunity is the first.
Atlas of Immunology
Swan Iowa State University. Guest editor for this symposium was W. William R.
In Western society, it was not until the late eighteenth century that a rational approach to the origin of disease developed. Prior to the discovery that disease was the result of pathogenic organisms, it was commonly accepted that disease was a punishment from God or the Gods , or even a witches curse. Eastern cultures perceived disease as an imbalance in the energy channels within the body. Later, the great plagues of Europe were assumed the result of virulent or noxious vapors. Nevertheless, there were intimations as early as B. However, this was never recognized as evidence of some type of internal defense system until the later part of the seventeenth century.
Written by an immunologist, A History of Immunology traces the concept of immunity from ancient times up to the present day, examining how changing concepts and technologies have affected the course of the science. It shows how the personalities of scientists and even political and social factors influenced both theory and practice in the field. With fascinating stories of scientific disputes and shifting scientific trends, each chapter examines an important facet of this discipline that has been so central to the development of modern biomedicine. With its biographical dictionary of important scientists and its lists of significant discoveries and books, this volume will provide the most complete historical reference in the field. Immunologists, molecular biologists, hematologists, historians of medicine and of science, individuals working in infectious disease. Theories of Acquired Immunity 2. Cellular vs.
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Чтобы увидеть, как какой-то молодой профессор украл его мечту. Стратмор холил и лелеял Сьюзан, оберегал. Он заслужил. И теперь наконец ее получит. Сьюзан будет искать защиту у него, поскольку ей негде больше будет ее найти.
Сьюзан оставила это замечание без ответа. - У правительств должно быть право собирать информацию, в которой может содержаться угроза общественной безопасности. - Господи Иисусе! - шумно вздохнул Хейл. - Похоже, Стратмор здорово промыл тебе мозги.
У Мидж отвисла челюсть. - Извините, сэр… Бринкерхофф уже шел к двери, но Мидж точно прилипла к месту. - Я с вами попрощался, мисс Милкен, - холодно сказал Фонтейн. - Я вас ни в чем не виню. - Но, сэр… - заикаясь выдавила .
Насколько опасен вирус. Джабба пристально посмотрел на директора и вдруг разразился смехом. - Вирус? - Его грубый хохот разнесся по подземелью.
Она превозмогала боль сколько могла, но ее силы иссякли. Она сказала ему, что их брак исчерпал себя, что она не собирается до конца дней жить в тени другой женщины. Вой сирен вывел его из задумчивости.
Но Цифровая крепость никогда не устареет: благодаря функции меняющегося открытого текста она выдержит людскую атаку и не выдаст ключа. Новый стандарт шифрования. Отныне и навсегда. Шифры, которые невозможно взломать. Банкиры, брокеры, террористы, шпионы - один мир, один алгоритм.
Он должен настичь Дэвида Беккера.
Среднее время, потраченное на один шифр, - чуть более шести минут. Потребление энергии на среднем уровне. Последний шифр, введенный в ТРАНСТЕКСТ… - Она замолчала.
Все это выглядит довольно странно. - Думаешь, надо вернуть им отчет. Она посмотрела на него недовольно.
ТО: NDAKOTAARA. ANON. ORG FROM: ETDOSH1SHA. EDU И далее текст сообщения: ГРОМАДНЫЙ ПРОГРЕСС. ЦИФРОВАЯ КРЕПОСТЬ ПОЧТИ ГОТОВА.
Если вы по глупости упадете, то это будет ваша личная глупость, кто бы ни придумал эти ступени.